segregatr: Segregation Analysis for Variant Interpretation

An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>, and further popularised by Bayrak-Toydemir et al. (2008) <doi:10.1016/j.yexmp.2008.03.006>. This implementation allows custom penetrance values and liability classes, and includes specialised pedigree visualisations.

Version: 0.3.0
Depends: pedtools (≥ 2.2.0), R (≥ 4.1.0)
Imports: pedprobr
Suggests: testthat
Published: 2023-06-26
DOI: 10.32614/CRAN.package.segregatr
Author: Magnus Dehli Vigeland ORCID iD [aut, cre], Christian Carrizosa ORCID iD [aut]
Maintainer: Magnus Dehli Vigeland <m.d.vigeland at>
License: GPL-3
NeedsCompilation: no
Language: en-GB
Materials: README NEWS
CRAN checks: segregatr results


Reference manual: segregatr.pdf


Package source: segregatr_0.3.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): segregatr_0.3.0.tgz, r-oldrel (arm64): segregatr_0.3.0.tgz, r-release (x86_64): segregatr_0.3.0.tgz, r-oldrel (x86_64): segregatr_0.3.0.tgz
Old sources: segregatr archive

Reverse dependencies:

Reverse imports: pedsuite


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