PMAPscore: Identify Prognosis-Related Pathways Altered by Somatic Mutation

We innovatively defined a pathway mutation accumulate perturbation score (PMAPscore) to reflect the position and the cumulative effect of the genetic mutations at the pathway level. Based on the PMAPscore of pathways, identified prognosis-related pathways altered by somatic mutation and predict immunotherapy efficacy by constructing a multiple-pathway-based risk model (Tarca, Adi Laurentiu et al (2008) <doi:10.1093/bioinformatics/btn577>).

Version: 0.1.1
Depends: R (≥ 4.1.0)
Imports: base, clusterProfiler, glmnet, graphics, grDevices, maftools,, pROC, stats, survival, survminer, utils
Suggests: knitr, rmarkdown
Published: 2022-04-12
DOI: 10.32614/CRAN.package.PMAPscore
Author: Junwei Han [aut, cre, cph], Yalan He [aut], Xiangmei Li [aut]
Maintainer: Junwei Han <hanjunwei1981 at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: PMAPscore results


Reference manual: PMAPscore.pdf
Vignettes: PMAPscore


Package source: PMAPscore_0.1.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): PMAPscore_0.1.1.tgz, r-oldrel (arm64): PMAPscore_0.1.1.tgz, r-release (x86_64): PMAPscore_0.1.1.tgz, r-oldrel (x86_64): PMAPscore_0.1.1.tgz
Old sources: PMAPscore archive


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